Endocrine Abstracts

Currently, most Type 2 Diabetes (T2D) treatments are targeted for the mitigation of the disease rather than remission. It has been previously demonstrated that T2D remission post-bariatric surgery in mice is independent of weight loss, indicating a metabolic mechanism. One avenue that remains largely unexplored is the role of cortisol, a hormone secreted from the adrenal cortex, dysregulation of which is linked to insulin resistance and obesity. The enzyme 11β-Hydroxyster...